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Synthetic Capsules Made of Natural Building Blocks

(PhysOrg.com) -- The basis of all life forms are vesicles: membrane-enclosed, liquid-filled “bubbles” made of lipids, proteins, and carbohydrates. Cells, which are separated from the surrounding medium...

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Gene called flower missing link in vesicle uptake in neurons

As part of the intricate ballet of synaptic transmission from one neuron to the next, tiny vesicles - bubbles containing the chemical neurotransmitters that make information exchange possible -- travel...

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When It Comes to Drug Delivery, Size Matters

(PhysOrg.com) -- One of the great promises of nanotechnologies lies in its ability to create drug-containing nanoparticles decorated with targeting molecules that recognize and bind to cancer cells,...

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Vaccine with no jab: Protein vaccines for needle-free immunization through...

(PhysOrg.com) -- Most immunizations currently involve an injection in the arm. In the future, vaccination may be accomplished without the unpleasant jab of a needle: a team led by Victor C. Yang at the...

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Researchers COMMAND a Better Class of Liposomes

(PhysOrg.com) -- Pop a bubble while washing the dishes and you're likely to release a few drops of water trapped when the soapy sphere formed. A few years ago, researchers at the National Institute of...

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Chemists mimic library of bio-membranes for use in nanomedicine, drug delivery

An international collaboration led by chemists and engineers from the University of Pennsylvania has prepared a library of synthetic biomaterials that mimic cellular membranes and that show promise in...

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Researchers develop drug delivery system using nanoparticles triggered by...

A new system for the controlled delivery of pharmaceutical drugs has been developed by a team of University of Rhode Island chemical engineers using nanoparticles embedded in a liposome that can be...

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All the same size: Assembly of uniformly pure protein microparticles using...

(PhysOrg.com) -- Proteins are an interesting class of drugs because they demonstrate high biological activity and are highly specific in their effects. It has become possible to produce more and more...

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Invention could improve cancer drug delivery, lessen harmful effects of...

(PhysOrg.com) -- An invention by University of Arizona researchers may provide a way to deliver chemotherapeutic drugs to cancer tissues in controlled doses without harming healthy body cells.

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Nano-technology uses virus' coats to fool cancer cells

While there have been major advances in the detection, diagnosis, and treatment of tumors within the brain, brain cancer continues to have a very low survival rate in part to high levels of resistance...

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Ingested nanoparticle toxicity

Ingestion of commonly encountered nanoparticles at typical environmental levels is unlikely to cause overt toxicity, according to US researchers. Nevertheless there is insufficient evidence to...

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Study identifies safe delivery system for tricky yet potent anti-cancer...

Researchers at the University of California, San Diego School of Medicine have discovered a way to effectively deliver staurosporine (STS), a powerful anti-cancer compound that has vexed researchers...

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Chemists show life on Earth was not a fluke

How life came about from inanimate sets of chemicals is still a mystery. While we may never be certain which chemicals existed on prebiotic Earth, we can study the biomolecules we have today to give us...

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Capillary device significantly improves manufacture of quality liposomes

When the English author Sir Francis Bacon wrote "The world's a bubble" in 1629, it's a safe bet he wasn't thinking about microfluidics. However, for a research team led by scientists at the National...

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A possible alternative to antibiotics

Scientists from the University of Bern have developed a novel substance for the treatment of severe bacterial infections without antibiotics, which would prevent the development of antibiotic resistance.

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New Cancer Drug Delivery System Is Effective and Reversible

For cancer drug developers, finding an agent that kills tumor cells is only part of the equation. The drug also must spare healthy cells, and ideally its effects will be reversible to cut short any...

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National Jewish Health receives patent for liposome-based vaccine

(PhysOrg.com) -- National Jewish Health has received a US patent for a new kind of vaccine, which uses a small lipid bubble to deliver an antigen and DNA adjuvant.

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Experimental radioprotective drug safe for lung cancer patients: study

Patients with advanced non-small cell lung cancer can safely take an experimental oral drug intended to protect healthy tissue from the effects of radiation, according to a study led by researchers at...

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Dying brightly: Fluorescence lights up cells programmed to die

Programmed cell death, or apoptosis, occurs tens of millions of times every day in every human body. Researchers in South Korea have devised an easy method to detect apoptotic cells by fluorescence, as...

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Controlled and targeted release of drugs

(Phys.org)—Researchers have discovered a method that allows for the controlled release of an active agent on the basis of a magnetic nanovehicle. The research, conducted by EPFL, the Adolphe Merkle...

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